The purpose of this study was to compare two different staining techniques on mammalian cardiac muscle tissue.  The most commonly used staining series for histological sections is the hematoxylin and eosin (H&E) series and; therefore, this series was chosen as the standard for comparison to another staining technique.  Cardiac muscle is striated and stores glycogen which can be detected with the periodic acid-Schiff (PAS) staining technique.  Several tissue slides of cardiac muscle were prepared using a standard histological protocol and were divided into two separate groups for staining with H&E and PAS.  Photographs were taken of the tissue stained with both techniques and are described and compared.